The DuckTales comic book published by Gladstone Publishing was the first of three different comic books based on the series of the same name. It ran for thirteen issues from July 1988 to February 1990, after which it was replaced by the DuckTales comic book published byDisney Comics.

Each issue of Gladstone's DuckTales comic featured at least one story based specifically on the show, and many issues also contained reprints of older Uncle Scrooge stories written and drawn by Carl Barks. The first two issues contained stories adapted from the episodes "Armstrong" and "Jungle Duck", with reprints of two Barks stories that had been adapted into DuckTales episodes, "The Lost Crown of Genghis Khan" and "The Giant Robot Robbers".

From issue 3 to issue 12, the comic also included a guide featuring descriptions of every episode from the show's first two seasons, listed in production order, with an appendix listing which episodes were adaptations of Carl Barks stories.

When the Uncle Scrooge comic license was returned to Gladstone in 1993, they did not revive and continue the DuckTales book. However, several stories originally published in Gladstone's DuckTales comic (particularly those written by William Van Horn) would be reprinted in later issues of Uncle Scrooge published by Gladstone and Gemstone Publishing.